The role of monoclonal antibodies in neurological disorders.
نویسندگان
چکیده
mulTiple sClerosis In multiple sclerosis, autoreactive T cells cross the blood-brain barrier under the influence of proinflammatory cytokines and cellular adhesion molecules, resulting in an attack on myelin, with resulting inflammation, degeneration and demyelination. Given the multitude of interactions involved in the immunopathogenesis of multiple sclerosis, several immunological pathways may be targeted with highly specific and selective antibodies.
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ورودعنوان ژورنال:
- Medicine and health, Rhode Island
دوره 94 11 شماره
صفحات -
تاریخ انتشار 2011